the Secrets of the Ancient Peruvians
|Mate de Coca.
size 1 coca tea bag (1gm)
also 13 alkaloids: Papain, pectin, Globulin, Quinolin,
Benzoin, Inulin, Reserpin and other substances
to extensive research
MATE DE COCA:
CONTAINS MORE PROTEINS (19.9%)
THAN MEAT (19.4%)
- FAR MORE CALCIUM (2,191%)
THAN CONDENSED MILK
- RICHER IN VITAMIN B-1 (276%) THAN
- SATISFIED DIETARY ALLOWANCE FOR
OSPHOROUS, VITAMIN A,
B AND E.
The physical effects of MATE DE COCA are as
- INCREASED STAMINA.
- ABILITY TO GO LONG PERIODS
OF TIME WITHOUT FOOD.
- BLOCKED SENSE OF FATIGUE
- DECREASED NEED FOR SLEEP.
- MOOD ELEVATION.
DE COCA is a traditional remedy for:
- ALTITUDE OR MOUNTAIN SICKNESS
- STRESS (excellent!!)
- TREATING GASTROINTESTINAL
- ALLEVIATING IRRITATION AND
INFECTION OF THEVOCAL
- PREVENTING VERTIGO.
ARTERIAL PRESSURE AND THE METABOLISM OF
- ALLEVIATING DIARREA.
- IMPROVING SEXUAL PROWESS.
- RELIEVING COLDS, BRUISES, SORE JOINTS, MUSCLES.
- SWOLLEN FEET AND HEADACHES.
Coca The Divine and Sacred Herb of the Incas
new cocaine addiction therapy discover the Peruvian Teobaldo
Llosa M.D. member of the Peruvian Psychiatric Association. Who
devoted over twenty years to the study of the
Nutritional properties of the Coca.
The oral ingestion of coca, such as chewing coca or drinking
mate coca it is a way to provide strong nutritional ingredients
that contains vitamins and Minerals. But coca oral ingestion
Completely different than absorb coca true the nose or smoke
coca. If your drink the coca it does not damage the mucosal
tissue of the nose. Teobaldo Llosa show to world their research
book about cloridrate of cocaine addiction and how to cure it
with oral coca.
The Standard Low
Dose of Oral Cocaine: Used for Treatment of Cocaine Dependence
Teobaldo, Llosa, "The Standard Low Dose of Oral Cocaine:
Used for Treatment of Cocaine Dependence." Substance Abuse.
1994; 15(4): pp. 215-220.
Mate Coca (CCT) has been used for the treatment of cocaine dependence. Two previous reports found that treatment that
includes CCT can be successful in controlling relapse to cocaine
dependence. In the current study, CCT plus counseling was used
to treat cocaine dependence in 23 cocaine-addicted coca paste
smokers seeking treatment at an outpatient clinic in Lima, Peru.
Cocaine lapses fell from 4.35
times a month prior to treatment to 1.22 during treatment. Mean
abstinence increased from 32 days before treatment to 217.2
days during treatment. The current results support the effectiveness
of CCT for preventing relapse in cocaine-addicted patients.
Cocaine hydrochloride (in
capsules of gelatin) has been used to treat psychiatric symptoms
such as steep disturbances in depressive patients (1). Cocaine
alkaloid as contained in coca leaves (CCL) has been used as
an antifatigue agent, as a substitute for coffee, as a fast-acting
antidepressant, as an energizer, and as a substitute stimulant
to wean users of amphetamines and cocaine from those drugs (2,
3). Cocaine contained in coca leaves is well absorbed by the
gastrointestinal tract when coca leaves are ingested alone or
mixed with pudding (4), drunk as a coca infusion (5), or ingested
as coca tablets (6). Recently, oral cocaine administration has
been mentioned as a potential prophylactic treatment for cocaine
abuse (7), and previous reports have described the use of mate
coca (CCT) to decrease withdrawal and control relapse in cocaine
dependence (8, 9).
Methods of oral cocaine administration have included chewing
coca leaves, chewing coca gums, drinking infusions of coca
leaves (3), ingesting coca tablets (6), swallowing capsules
(1), and drinking coca tea (8, 9). The typical amount of cocaine
ingested orally ranges from 4.8 mg (9) to 200 mg per day (1).
When used to treat cocaine dependence, the period of use can
range from a few days (1) to 1 year or more (9).
Given the limited effectiveness of existing treatments for
relapse control in cocaine dependence, the objective of the
current study was to conduct a preliminary investigation to
evaluate the effectiveness of low doses of oral cocaine for
controlling the craving and relapse phenomena in cocaine dependence.
II. a. Subjects
II. b. Coca Paste Smoking
II. c. Coca Tea
II. d. Procedure
II. a. Subjects
Subjects were 23 chronic coca paste smokers who met DSM-III-R
criteria for the diagnosis of cocaine dependence. All subjects
were male and enrolled in outpatient treatment in Lima, Peru.
Subjects' mean age was 23.1 years (SD = 6.4 years). At the initiation
of treatment, the mean history of cocaine smoking was 2.7 years,
the mean number of cocaine (coca paste) cigarettes per use session
was 22.4 (SD = 14.9), the mean number of lapses per month was
4.3 (SD = 1.7), and the mean longest period of abstinence from
cocaine during the past year was 32 days (SD = 38.1).
Patients were instructed to ingest two bags of coca tea (CCT)
twice a day for 3 months or more. Each dose consisted of two
bags of CCT steeped in 180 ml of water, with sugar or honey
added as the patient desired. This regimen resulted in the ingestion
of approximately 17.68 mg of coca per day.
II. b. Coca Paste Smoking
Coca paste (CCP) has been the most common form of cocaine use
in Peru and other South American countries since the 1970s.
CCP is a powdery amorphous substance of complex composition.
Its litmus reaction is alkaline or basic. Coca paste is an intermediate
product in the production of cocaine hydrochloride. Substances
used to elaborate coca paste are coca leaves, kerosene, sulfuric
acid, ammonia, carbonates, and other impurities (10). Coca paste
is between 40 and 85% cocaine (11), with an average cocaine
content of 49.3% (12). Its chemical composition is more complex
than that of cocaine hydrochloride (CCH), free base (FRB), or
crack (CCK) (13).
Coca paste is smoked in cigarettes. Its initial onset of action
is 8-10 see, the duration of the "high" is 5-10 min,
and the average acute dose is 60-250 mg. Cocaine peak plasma
levels are 300-800 ng/ml, the bioavailability (percentage absorbed)
is 6-32% (11), and benzoylecgonine peak urine levels are (50,000
Typically, coca paste is mixed with tobacco and, occasionally,
with marijuana. Addicts take out more than one-half of the tobacco
in a cigarette, mix it with coca paste, and then refill the
cigarette with the mixture (14). Tobacco and marijuana also
have pharmacological effects and, therefore, cannot be considered
simply as filler materials (15).
In the treatment of cocaine abusers, the patient who is also
a cigarette smoker should be considered to be polyaddicted.
A typical CCP addict smokes an average of 20 cigarettes per
day (range, 6 to 50 cigarettes), with approximately 95 mg of
cocaine in each cigarette (range, 60.8 to 129.2 mg of cocaine).
Approximately 1900 mg of cocaine is consumed per day (range,
1200 to 2584 mg of cocaine). Typically, a coca paste cigarette
contains 4 mg of nicotine. Approximately 80 mg of nicotine is
consumed per day (17). It is possible that concomitant nicotine
addiction may contribute to the high rate of relapse among cocaine-dependent
patients whose preferred method of administration is coca paste
smoking (16); such patients often experience relapse binges
as frequently as at 1 week or less (14).
II. c. Coca Tea
Each regular coca tea (CCY) bag, as sold in supermarkets, contains
1 g of crushed coca leaves containing an average of 5.3 mg of
cocaine. When one bag is steeped in 180 ml of hot water for
3 min, 4.42 mg of cocaine is released (18).
II. d. Procedure
Patients involved in the study attended counseling sessions
every week during the three 3 months of the study and every
2 weeks during the last 9 months. Four patients that live outside
of Lima attended counseling sessions twice a month for the first
3 months and once a month during the last 9 months. In all sessions,
patients were accompanied by a relative who lived in the same
home and who provided collateral reports of patients' behavior
and use of coca tea. Twelve (52%) patients were married, but
only five of these patients lived with their wives.
Each time that the patients attended the sessions, they answered
yes or no to the following five questions concerning symptoms
of coca paste craving: (i) Do you think of coca paste several
times a day? (ii) Do you need or want coca paste? (iii) Do you
pursue coca paste ? (iv) Do you feet sick because of using coca
paste? and (v) Do you have personal troubles resulting from
your use of coca paste? Responses were summed (total number
of yes responses) to provide an index of cocaine craving.
No other medications were used by patients, except for occasional
anxiolytics at night for sleep, 100 mg phenytoin (one patient)
and 200 mg carbamazepine (one patient). All patients were permitted
to smoke regular cigarettes, drink coffee, or drink alcohol.
Furthermore, no patient met DSM-III-R criteria for a diagnosis
of alcoholism at the point of study entry.
Patients received a medical examination, including hematology,
blood chemistries, and urinalysis at the start of treatment.
All patients had two positive benzoylecgonine urine tests prior
to study entry. Only 60% of patients were administered monthly
urine drug tests during treatment, and 80% of patients who reported
abstinence from CCP demonstrated negative urines.
Table 1 presents patient-by-patient relapse and abstinence
data. After 1 year of treatment, the average number of relapses
per month across patients fell from 4.35 (SD = 1.71) prior to
CCT treatment to 1.22 (SD = 1.66) during CCT treatment (t test
= 7.58; p < 0.0001). The mean reported longest CCP abstinence
increased significantly, from 32 (SD 36.8) days before treatment
to 217.2 (SD 128. 1) days during treatment (t test 6.34; p <
0.0001). The mean retention time in treatment was 309 days (SD
= 105). Eighteen of the patients (78.3%) completed all 360 days
of treatment. Fifteen patients (65.2%) improved to the point
that they could maintain abstinence for the last 6 months or
more. Three patients (13.0%) were treatment failures (could
not maintain abstinence; relapsed several times during treatment,
mainly in the last months, but remained in treatment). Five
patients (21.7%) left the study before 270 days of treatment.
It should be noted that collateral reports in every case confirmed
the patients' self-reports of cocaine-related behavior.
Table I. Patient-by-Patient Results
Pt. No. ARPT ARDP* LAWF LADT
1 4 0 15 360 Improve
2 2 0 30 360 Improve
3 8 0.16 7 330 Improve
4 4 1.33 180 180 Improve
5 2 0.58 90 210 Fail
6 1 1. 30 30 Abandon
7 4 0.41 7 270 Improve
8 6 4.5 7 7 Abandon
9 6 2.7 14 45 Fail
10 3 0.3 14 240 Improve
11 4 3.0 14 10 Abandon
12 5 1.41 7 180 Fail
13 5 3.75 60 8 Abandon
14 4 0.25 40 300 Improve
15 3 0.16 30 300 Improve
16 4 0.16 30 330 Improve
17 4 0.41 20 300 Improve
18 4 0.16 20 300 Improve
19 6 0 7 360 Improve
20 4 0.66 14 300 Improve
21 6 6. 30 5 Abandon
22 3 0.41 40 300 Improve
23 8 0.66 30 270 Improve
X 4.35 1.22 32 217.2
SD 1.17 1.66 36.8 128.1
Note: ARPT, average number of relapses per month prior to treatment;
ARDT, average number of relapses during treatment; LAWT, longest
period (days) of attempted abstinence without treatment; LADT,
longest period (days) of abstinence during treatment.
*Obtained by dividing the total number of relapses experienced
during treatment by the total number of months retained in treatment.
All patients accepted coca tea as treatment, but 18 patients
(78.3%) agreed that they would have preferred to take the same
medication in capsules rather than in liquid. Craving questionnaire
scores dropped from 4.39 at the beginning of treatment to 1.47
during treatment. No medical or behavior abnormalities were
detected during treatment.
No commonly used medical treatment for the prevention of relapse
to cocaine dependence is particularly effective. Several treatments
has been evaluated in controlled studies including psychotherapy
(19), pharmacotherapy (20-23), neuroelectric therapy (24), and
psychosurgery (25, 26). Other interventions such as social policy
strategies, acupuncture, and religious or philosophical counseling
have not been evaluated in a controlled manner.
Anecdotal reports of the use of coca tea for the control of
craving in cocaine users have been published (8, 9). However,
this literature has not described the exact amount of cocaine
received by patients when drinking the coca tea infusion. The
current study is the first to examine the efficacy of a standard
low dose of cocaine alkaloid administered in regular coca tea
for the treatment of cocaine dependence.
The treatment was well accepted by the patients and their relatives.
No medically adverse effects were reported by the patients,
and patients showed fewer lapses, longer periods of abstinence,
and reduced craving than prior to treatment. These results suggest
the potential effectiveness of low doses of oral cocaine for
controlling craving and relapse in cocaine dependence.
In summary, this initial study attempted to control relapse
in cocaine dependence through the use of coca tea. The results
suggest that standard low doses of coca tea can be helpful in
treatment of cocaine dependence. Future studies should attempt
to examine the efficacy of cocaine tea for the treatment of
cocaine dependence in a more rigorous and controlled manner.
Post RM, Gillin JC, Wyatt RJ, Goodwinn FK: The effect of orally
administered cocaine on sleep of depressed patients. Psychopharmacologia
Carrol E: Coca: The plant and its use. NIDA Res Monogr 1977;
Weil AT: Coca leaf as a therapeutic agent. Am J Drug Alcohol
Abuse 1978; 5(l):75-86
Llosa T, Colmenares E, León E, Castro J, Montoya I, Preston
K, Gorelick DA: Positive urine abuscreen ontrak for benzoylecgonine
and effects after ingesting coca tea infusion or coca leaves.
NIDA Res Monogr Ser 1994; 141:375
Cone EJ, Jenkins AJ: Studies on coca tea. II. Positive urine
tests from drinking coca tea. Presented at the International
Association of Forensic Toxicologists (TIAF) meeting, Aug 15-20,
Llosa T, Colmenares E, Castañeda B, Arbaiza J: Positive
urine abuscreen ontrak for benzoylecgonine and effects after
ingesting coca tablets. Clin Addic Quim 1993; 4:14
Bagastra O, Forman LJ, Howeedy A, Whittle P: A potential vaccine
for cocaine abuse prophylaxis. Immunopharmacology 1992; 23:173-179
Siegel RK ElSohly MA, Plowman T, Rury PM, Jones RT: Cocaine
in Herbal Tea. JAMA 1986; 255:1 (Letter to Editor)
Llosa T: Coca: Uses and Abuses. COCADI, Lima: DESA; 1991
Morales-Vacca M: A laboratory approach to the control of cocaine
in Bolivia. Bull Narcot 1984; 36; 2:33-43
Verebey K, Gold MS: From coca leaves to crack: The effects of
dose and routes of administration in abuse liability. Psychiatr
Ann 1988; 18(9):513-520
Murrelle L, Magruded-Habib K, Saunders WB, Florenzano R, Torres
de Galvis Y: In: Madrigal E, ed. Consequences of Smoking a Potent
Cocaine Product: A Clinical Profile of 424 Basuca Abusers Presenting
for Treatment in Medellin, Colombia. OPS/WHO: Washington, DC;
Jerí FR, Perez JC: Dependencia a la Cocaína en
el Perú. Observaciones en un grupo de 616 pacientes (Cocaine
dependence in Peru. Study of a group of 616 patients), Monografía
de Investigación 4. CEDRO, Lima: Tarea; 1990
Llosa T: Chemistry and toxicology of coca pastes and coca paste
cigarettes smoking. Lima: DESA; 1994
Jeri R, Sanchez C, Del Pozo T, Fernandez M: The syndrome of
coca paste. J Psychoact Drugs 1992; 24(2):173-182
Henningfield JE: Pharmacologic basis and treatment of cigarette
smoking. J Clin Psychiat 1984; 45:12(2):24-34
Llosa T, Henningfield JE: Analysis of coca paste cigarettes.
Tobacco Control Int J 1993; 2(4):333
Jenkins AJ, Llosa T, Montoya I, Cone EJ: Studies on coca tea.
I. Identification of alkaloids in coca leaf. Presented at the
International Association of Forensic Toxicologists (TIAF) meeting,
Aug 15-20, 1993, Leipzig
Gawin FH, Ellinwood EH: Cocaine and other stimulants: Action,
abuse and treatment. N Engl J Med 1988; 318:1173-1182
Halikas JA, Crosby RD, Carlson GA: Current Pharmacotherapy practices
for Cocaine abuse. Ann Clin Psychiat 1991; 3:167-168
Tims FM, Leukefeld CG: Cocaine treatment: Research and clinical
perspectives. NIDA Res Monogr Ser 1993; 135
León E, Llosa T, Montoya, Kreiter, Preston, Gorelick
DA: Comparison of open-label pharmacotherapies for cocaine dependence.
NIDA Res Monogr Set 1994; 141:432
Montoya I, Andrade A, Llosa T, Tamayo O, Gorelick DA: Cross-cultural
comparison of treatment practices for cocaine dependence. Presented
at AMERSA meeting (book of abstracts), Nov 1992
Gariti P, Auriacombe M, Incmikoski R, McLellan AT, Patterson
L, Dhopesh V, Mezochow J, Patterson M, O'Brien C: A randomized
double-blind study of neuroelectric therapy in opiate and cocaine
detoxification. J Substance Abuse 1992; 4:299-308
Llosa T: Follow-up study of 28 coca paste addicts treated by
open cingulotomy. Presented at the VII World Congress of Psychiatry,
July 1983, Vienna
NIDA Experts Meeting: New brain operation for "coca paste"
addicts raises eyebrows here in light of NIDA research. Drug
Abuse Educ 1984; April-May:36
Super Vitamin "C"
Boost your immune system
Feel Great and Healthy with Maca Extract. Two times more powerful than any other Maca root
Omega 3, Omega 6 Omega 9 in just one Dose.
How To Preapare IT
One of the most common way to use herbs are in the form of
infusions basically it is the most easy way assimilate phytochemicals of a herb: It only requires a boiling water and the herb,
the dried herb or the filtrant tea bag into a cup then
fill the cup or container with boling water and cover
it and let it rest for some minutes before drinking. never use sugar or any other swetener for your beverage it may
change the chemical composition of the infusion.
is necessary to use boiling water and not hot
water because only the boiling will accelerate
the extraction of the natural nutritional susbtances of
Do not boil the tea bag or the infusion together or you
will loose the medicinal properties of the herb.
adversaries of Andean culture, who condemn the coca plant, with
a glass of whisky in one hand and a cigarette in the other, clamour
for its eradication and treat its producers as pariahs should
give a plain answer to the following questions: If alcoholism
is one of the greatest scourges in Europe and responsible for
the slow extermination of the indigenous populations in America,
why is the cultivation of the vine not eradicated, even though
the vine incarnates one of the elements of the old world's identity?
Since the tobacco habit is responsible for a huge number of victims
in consumer societies, why is it impossible to prohibit the growing
of tobacco? Obviously, no answers will be forthcoming.
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